Scientific Programme

The meeting will run from 2 pm on Monday, 10th September, to 4 pm on Thursday, 13th, with the two keynote lectures as bookends to the entire meeting (first and last speakers).

In between, highlights of the program include the opportunity for all poster presenters to give short platform talks to introduce their posters, and excellent occasions for networking and social interaction during the meeting.  In particular, Wednesday's dinner will be held as an evening reception within the beautiful Natural History Museum
, with drinks and light food arranged so that participants can mingle and view the exhibits.

   
   

DAY 1 

Monday 10 September

13.00 -14.00

REGISTRATION 

(Rooms may not be available until 14:00. The Lodge can take bags and store them until the rooms are ready, and they have allocated the MORELLI ROOM for this purpose, at no extra cost.)

14:00 -14.15

WELCOME

14.15 -15.15

OPENING KEYNOTE: Liz Robertson
TGFβ Signalling Pathways Governing Cell Lineage Commitment in the Early Mouse Embryo

   

15.15 -15.30

SHORT BREAK

   

SESSION 1

Setting the stage for dialogue, morphogenesis

15.30 -16.00

Invited Speaker 2: Kristen Panfilio
Insect extraembryonic development: interactions inside and outside of the egg

16.00 -16.30

Invited Speaker 3: Federica Bertocchini
Evolution of Amniotes: Insight from Reptiles

   

16.30 -17.00

COFFEE BREAK

   

SESSION 2

Development meets bioinformatics

17.00 -17.30

Invited Speaker 4: Sarah Teichmann
Immunogenomics One Cell at a Time

17.30 -18.00

Invited Speaker 5: Miguel Manzanares
Early Events Driving Cell Differentiation in the Mouse Preimplantation Embryo

18.00 -18.15

Selected Short Communication 1: Laura Banaszynski
Building an active enhancer to drive cell fate decisions

18.15 -18.30

Selected Short Communication 2: Irene Yan
Pre and post-transcriptional regulation of Cscratch2 gene expression in neural embryogenesis

   

18.30 -19.30

Drinks Reception

19.30


DINNER

   
   

  DAY 2

  Tuesday 11 September  

    

  SESSION 3a

  Lineage and potency

  9.00-9.30

  Invited Speaker 6: Véronique Azuara
  Balancing Cell Specification and Potency in Stem Cells and In the Early Mouse Embryo

  9.30-10.00

  Invited Speaker 7: Claire Chazaud
  Cell Lineage Specification in the Mouse Inner Cell Mass

  10.00-10.15

  Selected Talk 3: Nestor Saiz 
  Tissue size determines lineage specification in the mouse blastocyst

  10.15- 10.30

  Selected Talk 4: Ayaka Yanagida: FGF-mediated cell surface fluctuations drive early embryonic lineage segregation

    

  10.30-11.00

  COFFEE BREAK

    

  11.00-13.00

  ORAL SHORTS (poster authors present   
   ≤3 slides in 3 min, one after the other, no time for questions) see below for order of presentation

  13.00-14.00

  LUNCH

     

  14.00-16.00

  AFTERNOON ACTIVITIES:                       
  Punting/ Pubcrawling/ City walking tour

    

  SESSION 3b

  Lineage and potency

  16.00-16.30

  Invited Speaker 8: Takashi Hiiragi
  Self-Organisation in Mouse Development

  16.30-17.00

  Invited Speaker 9: Jennifer Nichols
  Perturbing Visceral Endoderm by Conditional Deletion of Oct4

  17.00-17.15

  Selected Talk 5: Matthew Stower
  Quantitative characterisation of tissue-wide cell behaviour during Anterior Visceral Endoderm migration using
  selective-plane imaging microscopy

  17.15-17.30

  Selected Talk 6: Go Shioi
  Global cell rearrangement in visceral endoderm during the A-P axis formation in a mouse embryo

      

  17.30-19.00

 
  POSTER SESSION 1/ LATE COFFEE BREAK

      

  19.30

 
  DINNER

   
   

 
  DAY 3

 
  Wednesday 12 September

    

 
  SESSION 4a

 
  Evolution and comparative development

  9.00-9.30

 
  Invited Speaker 10: Stephen Frankenberg
  The Evolution of Mammalian Extraembryonic Lineages

 
  9.30-10.00

 
  Invited Speaker 11: Berenika Plusa
  Differences in Extraembryonic Lineage Formation in Mammals

 
  10.00-10.15

 
  Selected Talk 7: Anna Ajduk
  Optical coherence microscopy as a novel, non-invasive method for the 4D live imaging of early mammalian embryos

 
  10.15-10.30

 
  Selected Talk 8: Monika Bialecka
  Human blastocyst outgrowths recapitulate primordial germ cell specification events

    

 
  10.30-11.00

 
  COFFEE BREAK

    

 
  SESSION 4b

 
  Evolution and comparative development

 
  11.00-11.15

 
   Selected Talk 9: Anna Piliszek
   Inner cell mass plasticity and trophectoderm differentiation in preimplantation rabbit embryo

 
  11.15-11.45

 
  Invited Speaker 12: James Turner
  Metatherian Embryo Single Cell Rna-Seq Reveals Conserved Principles of Mammalian Development and X-Dosage    Compensation

 
  11.45-12.15

 
  Invited Speaker 13: Siegfried Roth
  The Evolution of Dorsoventral Axis Formation in Insects

    

 
  12.15-13.15

 
  LUNCH

 
  13.15- 14.45

 
  POSTER SESSION 2/ COFFEE BREAK

  
  SESSION 5

 
  Extraembryonic interface


 
  14.45 - 15.15

 
  Invited Speaker 14: Rosalind John
  Genomic Conflict Over Placental Endocrine Lineages: Do Fathers Manipulate Motherly Love?


 
  15.15- 15.45

 
  Invited Speaker 15: Myriam Hemberger
  The Under-Appreciated Role of the Placenta as A Pivotal Target Organ for Reproductive Health

 
  15.45- 16.00

 
  Selected Talk 10: David Harrison
  Placental programming of offspring behaviour by a non-genetic mechanism.

 
  16.00-16.15

 
  Selected Talk 11: Jacinta Kalisch-Smith
  Periconceptional alcohol exposure causes female-specific perturbations to trophoblast differentiation and placental 
  formation.

    

 
  16.15 - 16.45

 
  COFFEE BREAK

    

 
  SESSION 6

 
  Epigenetics at the interface

 
  16.15-17.15

 
  Invited Speaker 16: Diana Laird
  Epigenetic Disruption of Fetal Germ Cells by Prenatal Exposures


 
  17.15-17.45

 
  Invited Speaker 17: Elizabeth Duncan
  Epigenetics, Plasticity and Reproductive Control in Insects: What Can Insects Tell Us About How Animals Respond t    to Their Environment?

    

 
  18.30

 
  EVENING SOCIAL RECEPTION
  Natural History Museum, drinks and light bites from 18:30

   
   

  DAY 4

  Thursday 13 September

    

  SESSION 7a

  Signalling and environmental interactions

  9.00-9.30

  Invited Speaker 18: Maurijn van der Zee
  The Extraembryonic Serosa Protects the Insect Egg against Pathogens and Desiccation

  9.30-9.45

  Selected Talk 12: Nora Braak
  How does a butterfly embryo cope with environmental stress?

  9.45-10.00

  Selected Talk 13: Di Hu
  Ets2 Regulates Apoptosis and Proliferation via Tissue-Specific Mechanisms in Early Mouse Embryogenesis

  10.00-10.15

  Selected Talk 14: Zofia Madeja
  Inhibitor mediated modulation of developmentally important signalling pathways affects the expression of lineage 
  specific factors in bovine preimplantation embryos

    

10.15-10.45

  COFFEE BREAK

    

  SESSION 7b

  Signalling in development

  10.45-11.15

  Invited Speaker 19: Vasso Episkopou
  Mechanism of Dose Dependent Functions Downstream of Nodal

  11.15-11.45

  Invited Speaker 20: Jaime Rivera
  Assessment of Pre-E9.5 Lethal Mutations and Generation of New Ones Using in Vivo Gene Editing

  11.45-12.00

  Selected Talk 15: Nicolas Porchet
  Roles of Nodal signaling on cell-fate specification in the preimplantation mouse embryo

  12.00-12.15

  Selected Talk 16: Elisabetta Ferretti
  Converting space and time into mesodermal fate

    

  12.15-13.15

  LUNCH

    

  13.15-13.45

  Dennis Summerbell award lecture: Mariya Dobreva
  Amniotic ectoderm expansion in mouse depends on Smad5-mediated signalling

  13.45-14.45

  CLOSING KEYNOTE: Ali Brivanlou
  Self-Organization of Spatial Patterns in Artificial 2d and 3d Human Embryos and Organoids

    

  14.45-15.00

  SHORT BREAK

    

  15.00-16.00

 
  CLOSING REMARKS, ANNOUNCEMENT OF POSTER
  PRIZE WINNERS, ROUND TABLE DISCUSSION

   
   

Poster Presenters
ORAL SHORTS (poster authors present ≤3 slides in 3 min, one after the other, no time for questions, see below for order of presentation)

 

Presenting Author

Title

P1

Peter Baillie-Johnson

Setting the stage for gastrulation: Contact with the extraembryonic basement membrane promotes epithelial organisation in gastruloids; an in vitro model system for early post-implantation development.

P2

Anahi Binagui-Casas

Exploring the role of Flk-1/Kdr in mesodermal derivatives of the post-gastrulation mouse embryo

P3

Raquel Boque Sastre

The imprinted Peg3 gene regulates placental hormones.

P4

Hugo Creeth

Maternal care boosted by paternal imprinting in mammals

P5

Katarzyna Filimonow

Klf family genes expression in preimplantation rabbit embryos

P6

Jessica Forsyth

Influence of the cell micro-environment during cell fate decisions in the pre-implantation mouse embryo

P7

Laina Freyer

Yolk sac-derived erythromyeloid progenitors in fetal liver myelopoiesis

P8

Kirstie Lawson

Clonal analysis of the development of the amniotic ectoderm in the mouse embryo

P9

Madeleine Linneberg-Agerholm

Characterising extra-embryonic primitive endoderm differentiation and expansion from naive human embryonic stem cells

P10

Cecília G. Magalhães

Filopodia-mediated intercellular vesicular exchange in the chick embryo

P11

Sophie Morgani

Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning

P12

Salvador Perez-Montero

Unravelling how p53 provides a competitive advantage during early embryonic development

P13

Dominique Peter

Establishment of a murine 3D cell culture model of the endometrium

P14

Fabian Pridoehl

LSFM imaging and 3D reconstruction as a new tool to investigate morphogenesis

P15

Alice Ramešová

Activation of caspase-8 during mandibular development suggests novel roles in craniofacial morphogenesis

P16

Connor Ross

Bananas about hypoblast: towards a functional model for hypoblast identity in primates

P17

Moumita Sarkar

Involvement of phosphorylation-mediated nuclear localisation of CNOT3 in mesoendodermal differentiation of mouse ES cells

P18

Stanley Strawbridge

FGF4-dependent population dynamics during embryonic stem cell incorporation into the murine chimera

P19

Lorna Sumption

Imprinted PEG3 domain disruption in association with prenatal depression

P20

Matthias Teuscher

Exploring polyploidy in the extraembryonic epithelia of the beetle Tribolium castaneum using two complementary methods

P21

Violeta Trejo

Defining the function of Smoc proteins during chick embryonic development

P22

Fumiko Usami

Planar cell polarity factors are differentially involved in polarity establishment of ciliary orientation and cell elongation in the mouse oviduct.

P23

Hui Ting Zhang

Axis specification and morphogenesis in mouse peri-implantation embryogenesis

P24

Berna Sozen

[late breaking!]

Self-assembly of embryonic and two extra-embryonic stem cell types to recapitulate early gastrulation in vitro